The weeks shown in color represent the start and end points of chemical exposure for each study.
|Study Results||Study Details||References|
Results for Bisphenol ADecreased uterine PR, ERα and Hoxa10 mRNA levels and decreased ERα protein levels on 5th day of pregnancy.
Subjects: Wistar rats
Chemical: Bisphenol A
Low doses tested: 0.5 mg/kg bw/d
Other doses tested: 20.0 mg/kg bw/d
Route of administration: dissolved in corn oil and delivered subcutaneously
Exposure duration: post-natal day 1 – post-natal day 7 (comparable to human prenatal development from approximately day 1 of week 20 to day 1 of week 28)
Age of measurement: post-natal weeks 12-16
|Reference [PubMed Link]
Varayoud J, Ramos JG, Bosquiazzo VL, Lower M, Munoz-de-Toro M, Luque EH. 2011. Neonatal exposure to bisphenol A alters rat uterine implantation-associated gene expression and reduces the number of implantation sites. Endocrinology 152(3):1101-1111.